Solvent Users Look to Replace NMP Solvents
November 17, 2025
In 2017, the
U.S. Environmental Protection Agency (EPA) proposed a usage ban for N-Methyl pyrrolidone, also known as NMP, due to its classification as a developmental toxicant. Primarily used in paint strippers, coatings, and adhesives, NMP is still widely used, as the proposal was shelved under pressure. However, more solvent users are continuing to replace NMP solvents on their own, making powerful and cost-effective alternatives even more important. Below, we will explore a few of the options and why you should consider them as viable replacements for your NMP solvents.
Why Solvent Users are Looking to Replace N-Methylpyrrolidone (NMP)
N-Methylpyrrolidone (NMP) has been widely used in coatings, adhesives, and paint strippers for its strong solvency. But growing concerns about its health and environmental risks are pushing many companies to find safer, more sustainable alternatives.
Solvent users looking to replace NMP solvents now have access to high-performing bio-based options that match or exceed the performance of traditional petrochemical products, without the regulatory or safety concerns.
Health Risks
NMP poses serious health concerns, particularly related to reproductive toxicity and long-term organ damage. Even short-term exposure can cause skin, eye, and respiratory irritation.
Reducing these risks is a key reason solvent users are seeking safer, more responsible alternatives.
Short-Term Acute Exposure
Even brief exposure to NMP can lead to serious health risks. According to the EPA, over 11,000 pregnant consumers and 160 pregnant workers are at increased risk of miscarriage or stillbirth each year due to NMP exposure. These risks may also impact future pregnancies and child development.
Short-term contact can also cause skin, eye, and respiratory irritation, raising immediate safety concerns in the workplace.
Long-Term Chronic Exposure
Prolonged or repeated exposure to NMP has been linked to several chronic health effects. These include reductions in body weight, kidney and liver toxicity, reproductive harm, and potential neurotoxicity.
Over time, continued use of NMP can pose serious risks to both workers and end users, making long-term exposure an important factor in the push for safer alternatives.
Safety Concerns
In addition to health risks, NMP poses several safety challenges in industrial environments. Its low flash point and ability to absorb through the skin increase the chances of accidents and unintentional exposure during routine handling.
Because of these factors, many companies are exploring solvent options that are easier to manage safely while still delivering reliable performance.
Regulatory Scrutiny
NMP continues to face increasing regulatory attention. Although a proposed EPA ban was delayed, the solvent remains under active review due to its toxicity profile.
Internationally, NMP is listed as a substance of very high concern (SVHC) under REACH regulations in the European Union, triggering usage restrictions and reporting requirements. Ongoing scrutiny makes it a potential liability for manufacturers that rely on global distribution or operate in tightly regulated industries.
Economic Benefits of Switching from NMP
Transitioning away from N-Methyl pyrrolidone (NMP) to safer alternatives offers compelling economic advantages. Companies can realize significant cost savings, improve operational efficiency, and enhance their environmental and social responsibility. Specifically:
- Reduced costs in PPE
- Avoid fines and penalties with environmental regulations
- Stable pricing for bio-based solvents
- Enhanced brand reputation
Are Other Groups Also Trying to Phase Out NMP?
While the EPA has delayed action on NMP solvents, many top retailers are working to halt the sale of these products. For example, Lowe’s and The Home Depot stopped selling paint strippers with NMP in 2018, and Sherwin-Williams no longer carries products with NMP. Additionally, the European Union currently places NMP on its restricted substance list.
Bio-Based Solvents as an NMP Alternative
Bio-based solvents are gaining traction as effective, safer alternatives to NMP. With strong solvency power and broad formulation compatibility, they help reduce exposure risks while meeting performance demands in industrial applications.
Solvent users looking to replace NMP solvents are increasingly choosing plant-derived options that align with evolving safety standards and sustainability goals. Vertec BioSolvents offers two solutions that make this transition simple and cost-effective.
Vertec Bio ELSOL NMPR
VertecBio ELSOL NMPR is a 100 percent biodegradable, non-carcinogenic solvent and an ideal NMP alternative for cleaning applications. It contains no hazardous air pollutants (HAPs), no environmentally hazardous ingredients, and no substances of concern.
This formulation is especially effective for cleaning polyurethanes and performs well in paints, coatings, and ink systems.
Vertec Bio ELSOL NMPRx3
VertecBio ELSOL NMPRx3 is a versatile bio-based solvent blend designed to replace NMP in a wide range of formulations. It offers excellent solvency for paints, coatings, and ink applications.
Custom blends are also available to ensure optimal performance for your specific needs.
Vertec Bio Solvents – Helping You Replace NMP and More
At Vertec BioSolvents, we’re committed to helping you transition to safer, high-performing solutions without compromising results. Our bio-based solvents meet the demands of industrial applications while promoting safer workplaces and sustainable operations.
If you're looking to replace NMP or eliminate other petroleum-based solvents, we provide alternatives that align with your technical needs and environmental goals. Contact us today to learn how we can help you move forward with confidence.
